Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium.

Mechanisms of development - 1 Nov 2004

Jonker Leon, Kist Ralf, Aw Andrew, Wappler Ilka, Peters Heiko

Abstract excerpt

The epidermis is a derivative of the surface ectoderm. It forms a protective barrier and specific appendages including hair, nails, and different eccrine glands. The surface ectoderm also forms the epithelium of the oral cavity and tongue, which develop a slightly different barrier and form different appendages such as teeth, filiform papillae, taste papillae, and salivary glands. How this region-specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Polarity
Share to Epithelium
Share to Keratins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Paired Box Transcription Factors

Share to PAX9 Transcription Factor

Share to Tongue

Source

Identifiers

PMID: 15454262
DOI: 10.1016/j.mod.2004.07.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium.PMID 15454262Read ↗

The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells.Semantic proximity Read ↗

Keratin 13 deficiency causes white sponge nevus in mice.Semantic proximity Read ↗

Making sense of the epithelial barrier: what molecular biology and genetics tell us about the functions of oral mucosal and epidermal tissues.Semantic proximity Read ↗

Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasiaSemantic proximity Read ↗

WT1 regulates the development of the posterior taste field.Semantic proximity Read ↗

The Pax9/Wnt pathway regulates secondary palate formation in miceSemantic proximity Read ↗

Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.Semantic proximity Read ↗

Impairing squamous differentiation by Klf4 deletion is sufficient to initiate tongue carcinoma development upon K-Ras activation in mice.Semantic proximity Read ↗

Sox2 is required for development of taste bud sensory cells.Semantic proximity Read ↗

The bicistronic gene würmchen encodes two essential components for epithelial development in Drosophila.Semantic proximity Read ↗

Pax9's dual roles in modulating Wnt signaling during murine palatogenesis.Semantic proximity Read ↗

Single-cell RNA-seq identifies a reversible epithelial-mesenchymal transition in abnormally specified epithelia of p63 EEC syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.