Article
GPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation.
The Journal of biological chemistry - 10 Dec 2004
Fujita Morihisa, Yoko-o Takehiko, Okamoto Michiyo, Jigami Yoshifumi
Abstract excerpt
GPI7 is involved in adding ethanolaminephosphate to the second mannose in the biosynthesis of glycosylphosphatidylinositol (GPI) in Saccharomyces cerevisiae. We isolated gpi7 mutants, which have defects in cell separation and a daughter cell-specific growth defect at the non-permissive temperature. WSC1, RHO2, ROM2, GFA1, and CDC5 genes were isolated as multicopy suppressors of gpi7-2 mutant. Multicopy...
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