Article
Atf1-Pcr1-M26 complex links stress-activated MAPK and cAMP-dependent protein kinase pathways via chromatin remodeling of cgs2+.
The Journal of biological chemistry - 3 Dec 2004
Davidson Mari K, Shandilya Harish K, Hirota Kouji, Ohta Kunihiro, Wahls Wayne P
Abstract excerpt
Although co-ordinate interaction between different signal transduction pathways is essential for developmental decisions, interpathway connections are often obscured and difficult to identify due to cross-talk. Here signals from the fission yeast stress-activated MAPK Spc1 are shown to regulate Cgs2, a negative regulator of the cAMP-dependent protein kinase (protein kinase A) pathway. Pathway integration is...
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