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Article

Interferon‐γ Expression in Periventricular Leukomalacia in the Human Brain

1 Jul 2004

Abstract excerpt

Periventricular leukomalacia (PVL), the major lesion underlying cerebral palsy in survivors of prematurity, is characterized by focal periventricular necrosis and diffuse gliosis of immature cerebral white matter. Causal roles have been ascribed to hypoxiaischemia and maternal-fetal infection, leading to cytokine responses, inflammation, and oligodendrocyte cell death. Because interferon-gamma (IFN-gamma) is...

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Identifiers

PMID: 15446581
DOI: 10.1111/j.1750-3639.2004.tb00063.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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