Article
The association of lumbar spondylolisthesis with collagen IX tryptophan alleles.
The Journal of bone and joint surgery. British volume - 1 Sept 2004
Matsui Y, Mirza S K, Wu J J, Carter B, Bellabarba C, Shaffrey C I, Chapman J R, Eyre D R
Abstract excerpt
Two collagen type IX gene polymorphisms that introduce a tryptophan residue into the protein's triple-helical domain have been linked to an increased risk of lumbar disc disease. To determine whether a particular subset of symptomatic lumbar disease is specifically associated with these polymorphisms, we performed a prospective case-control study of 107 patients who underwent surgery of the lumbar spine. Patients...
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