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Article

Matrix deposition of tryptophan-containing allelic variants of type IX collagen in developing human cartilage.

Matrix biology : journal of the International Society for Matrix Biology - 1 Apr 2003

Matsui Yoshito, Wu Jiann-Jiu, Weis Mary Ann, Pietka Terri, Eyre David R

Abstract excerpt

Genetic polymorphisms that encode a tryptophan (Trp) residue in the triple-helical domain of the alpha2 (Trp2) or alpha3 chain (Trp3) of human type IX collagen have been linked to risk of degenerative intervertebral disc disease. To determine whether these two allelic variants express protein that may affect the extracellular matrix of cartilage in vivo, we examined the properties of resident type IX collagen in...

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Identifiers

PMID: 12782139
DOI: 10.1016/s0945-053x(02)00102-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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