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Article

Food-derived mutagens and carcinogens.

Cancer research - 1 Apr 1992

Wakabayashi K, Nagao M, Esumi H, Sugimura T

Abstract excerpt

Cooked food contains a variety of mutagenic heterocyclic amines. All the mutagenic heterocyclic amines tested were carcinogenic in rodents when given in the diet at 0.01-0.08%. Most of them induced cancer in the liver and in other organs. It is noteworthy that the most abundant heterocyclic amine in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, produced colon and mammary carcinomas in rats and...

Topics

Amines
Animals
Carcinogenicity Tests
Carcinogens
DNA
Drug Synergism
Food
Hot Temperature
Mice
Mutagenicity Tests
Mutagens
Mutation
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Salmonella typhimurium

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Identifiers

PMID: 1544146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1544146-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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