Article
HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay.
AIDS (London, England) - 1 Jan 1992
Koot M, Vos A H, Keet R P, de Goede R E, Dercksen M W, Terpstra F G, Coutinho R A, Miedema F, Tersmette M
Abstract excerpt
OBJECTIVE: We have previously demonstrated that detection of syncytium-inducing (SI) HIV-1 in asymptomatic seropositive individuals is associated with rapid progression to AIDS. In the present study, we sought to develop and evaluate an HIV-1 phenotyping assay for the screening of large numbers of individuals. METHODS: Efficiency of HIV-1 isolation from patient peripheral blood mononuclear cells (PBMC) was...
Topics
- Acquired Immunodeficiency Syndrome
- Cell Line
- Cells, Cultured
- Giant Cells
- HIV Infections
- HIV-1
- Humans
- Monocytes
- Phenotype
- T-Lymphocytes
- Virus Replication
