Identification of propafenone metaboliser phenotype from plasma and urine excretion data.

doi:10.1007/BF00314930

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Article

Identification of propafenone metaboliser phenotype from plasma and urine excretion data.

European journal of clinical pharmacology - 1 Jan 1992

Latini R, Belloni M, Bernasconi R, Cappiello E, Giani P, Landolina M, Leopaldi D, Castel J M

Abstract excerpt

The aim of the study was to validate a test based on analyses of urine to identify the propafenone metaboliser phenotype during routine chronic therapy. Twenty seven patients chronically treated with propafenone were studied. A debrisoquine test was performed in 10. Propafenone and its metabolite...

Topics

Adolescent
Adult
Aged
Arrhythmias, Cardiac
Child
Debrisoquin
Female
Humans
Hydroxylation
Male
Middle Aged
Phenotype
Propafenone

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