Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements.

Genes, chromosomes & cancer - 1 Dec 2004

Kobzev Yuri N, Martinez-Climent Jose, Lee Sanggyu, Chen Jianjun, Rowley Janet D

Abstract excerpt

The NUP98 gene has been reported to be fused with at least 15 partner genes in leukemias with 11p15 translocations. We report the results of screening of cases with cytogenetically documented rearrangements of 11p15 and the subsequent identification of involvement of NUP98 and its partner genes. We identified 49 samples from 46 hematology patients with 11p15 (including a few with 11p14) abnormalities, and using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 11
Share to DNA Topoisomerases, Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine Nucleotide Exchange Factors

Share to Homeodomain Proteins

Share to In Situ Hybridization, Fluorescence

Share to Leukemia

Share to Nuclear Pore Complex Proteins

Share to Translocation, Genetic

Source

Identifiers

PMID: 15390187
DOI: 10.1002/gcc.20092

Genes

NUP98
HOXC13
HOXD13
PRRX1
TOP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements.PMID 15390187Read ↗

The inv(11)(p15q22) Chromosome Translocation of De Novo and Therapy-Related Myeloid Malignancies Results in Fusion of the Nucleoporin Gene, NUP98, With the Putative RNA Helicase Gene, DDX10Semantic proximity Read ↗

NUP98 is fused to HOXA9 in a variant complex t(7;11;13;17) in a patient with AML-M2.Semantic proximity Read ↗

The t(11;20)(p15;q11) Chromosomal Translocation Associated With Therapy-Related Myelodysplastic Syndrome Results in anNUP98-TOP1 FusionSemantic proximity Read ↗

POU1F1 is a novel fusion partner of NUP98 in acute myeloid leukemia with t(3;11)(p11;p15)Semantic proximity Read ↗

NUP98 Is Fused to PMX1 Homeobox Gene in Human Acute Myelogenous Leukemia With Chromosome Translocation t(1;11)(q23;p15)Semantic proximity Read ↗

NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15)Semantic proximity Read ↗

NUP98 dysregulation in myeloid leukemogenesis.Semantic proximity Read ↗

NUP98/11p15 translocations affect CD34+ cells in myeloid and T lymphoid leukemias.Semantic proximity Read ↗

Clinical whole-genome sequencing identifies NSD3 as the correct fusion partner of NUP98 in a patient with acute myeloid leukemia and t(8;11)(p11.2;p15): a case reportSemantic proximity Read ↗

NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.Semantic proximity Read ↗

Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias withHOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15)Semantic proximity Read ↗

Acute myeloid leukemia with NUP98-HOXC13 fusion and FLT3 internal tandem duplication mutation: case report and literature review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.