Article
Association of genetic variants of GRIN2B with autism.
Scientific reports - 6 Feb 2015
Pan Yongcheng, Chen Jingjing, Guo Hui, Ou Jianjun, Peng Yu, Liu Qiong, Shen Yidong, Shi Lijuan, Liu Yalan, Xiong Zhimin, Zhu Tengfei, Luo Sanchuan, Hu Zhengmao, Zhao Jingping, Xia Kun
Abstract excerpt
Autism (MIM 209850) is a complex neurodevelopmental disorder characterized by social communication impairments and restricted repetitive behaviors. It has a high heritability, although much remains unclear. To evaluate genetic variants of GRIN2B in autism etiology, we performed a system association study of common and rare variants of GRIN2B and autism in cohorts from a Chinese population, involving a total...
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