Article
Genetic polymorphisms among human cytomegalovirus (HCMV) wild-type strains.
Reviews in medical virology - 1 Jan 2000
Pignatelli Sara, Dal Monte Paola, Rossini Giada, Landini Maria Paola
Abstract excerpt
Human cytomegalovirus (HCMV) clinical isolates display genetic polymorphisms in multiple genes. Some authors have suggested that those polymorphisms may be implicated in HCMV-induced immunopathogenesis, as well as in strain-specific behaviours, such as tissue-tropism and ability to establish persistent or latent infections. This review summarises the features of the main clustered HCMV polymorphic open reading...
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