Lack of associations between HLA class II alleles and resistance to HIV-1 infection among white, non-Hispanic homosexual men.

doi:10.1097/01.qai.0000127026.47429.5c

Article

Lack of associations between HLA class II alleles and resistance to HIV-1 infection among white, non-Hispanic homosexual men.

Journal of acquired immune deficiency syndromes (1999) - 1 Oct 2004

Liu Chenglong, Carrington Mary, Kaslow Richard A, Gao Xiaojiang, Rinaldo Charles R, Jacobson Lisa P, Margolick Joseph B, Phair John, O'Brien Stephen J, Detels Roger

Abstract excerpt

HLA class II alleles were molecularly typed for 100 high-risk seronegative men and 184 low-risk seroconverters from the Multicenter AIDS Cohort Study (MACS). Seven resistant individuals homozygous for CCR5 Delta32 deletions were excluded from analysis. In the univariate analysis, no significant HLA class II associations with resistance/susceptibility to HIV type 1 infection were identified. However, the...

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Lack of associations between HLA class II alleles and resistance to HIV-1 infection among white, non-Hispanic homosexual men.

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