Article
Erythrocyte invasion phenotypes of Plasmodium falciparum in The Gambia.
Infection and immunity - 1 Apr 2003
Baum Jake, Pinder Margaret, Conway David J
Abstract excerpt
In vitro experimentation with Plasmodium falciparum has determined that a number of different receptor-ligand interactions are involved in the invasion of erythrocytes. Most culture-adapted parasite isolates use a mechanism of invasion that depends primarily on the erythrocyte sialoglycoprotein glycophorin A (GYPA) and erythrocyte-binding antigen 175 (EBA-175) of the parasite blood-stage merozoite. However, a...
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