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Article

Blood donor variability is a modulatory factor for P. falciparum invasion phenotyping assays.

Scientific reports - 29 Mar 2021

Thiam Laty G, Nyarko Prince B, Kusi Kwadwo A, Niang Makhtar, Aniweh Yaw, Awandare Gordon A

Abstract excerpt

Human erythrocytes are indispensable for Plasmodium falciparum development. Unlike other eukaryotic cells, there is no existing erythroid cell line capable of supporting long-term P. falciparum in vitro experiments. Consequently, invasion phenotyping experiments rely on erythrocytes of different individuals. However, the contribution of the erythrocytes variation in influencing invasion rates remains unknown,...

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PMID: 33782439
DOI: 10.1038/s41598-021-86438-1
PMCID: PMC8007732

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ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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