Article
Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN).
Trends in parasitology - 1 Apr 2016
Ahouidi Ambroise D, Amambua-Ngwa Alfred, Awandare Gordon A, Bei Amy K, Conway David J, Diakite Mahamadou, Duraisingh Manoj T, Rayner Julian C, Zenonos Zenon A
Abstract excerpt
Erythrocyte invasion by Plasmodium falciparum merozoites is an essential step for parasite survival and proliferation. Invasion is mediated by multiple ligands, which could be promising vaccine targets. The usage and sequence of these ligands differs between parasites, yet most studies of them have been carried out in only a few laboratory-adapted lines. To understand the true extent of natural variation in...
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