Article
The Ton system, an ABC transporter, and a universally conserved GTPase are involved in iron utilization by Brucella melitensis 16M.
Infection and immunity - 1 Oct 2004
Danese Isabelle, Haine Valerie, Delrue Rose-May, Tibor Anne, Lestrate Pascal, Stevaux Olivier, Mertens Pascal, Paquet Jean-Yves, Godfroid Jacques, De Bolle Xavier, Letesson Jean-Jacques
Abstract excerpt
Brucella spp. are gram-negative intracellular facultative pathogens that are known to produce 2,3-dihydroxybenzoic acid (DHBA), a catechol siderophore that is essential for full virulence in the natural host. The mechanism of DHBA entry into Brucella and other gram-negative bacteria is poorly understood. Using mini-Tn5Kmcat mutagenesis, we created a transposon library of Brucella melitensis 16M and isolated 32...
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