Article
Expression of vascular endothelial growth factor receptor-2 or Tie-2 on peripheral blood cells defines functionally competent cell populations capable of reendothelialization.
Circulation - 14 Dec 2004
Nowak Grzegorz, Karrar Azza, Holmén Carolina, Nava Silvia, Uzunel Mehmet, Hultenby Kjell, Sumitran-Holgersson Suchitra
Abstract excerpt
BACKGROUND: Receptor tyrosine kinases that include vascular endothelial growth factor (VEGFR)-1, VEGFR-2, and Tie-2 regulate cardiovascular development and physiological and pathological angiogenesis. We were interested in the phenotypic and functional characterization of peripheral blood cells expressing these receptors and their therapeutic potential in vascular injury. METHODS AND RESULTS: VEGFR-1+, VEGFR-2+,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.