Article
ACE1 polymorphism and progression of SARS.
Biochemical and biophysical research communications - 22 Oct 2004
Itoyama Satoru, Keicho Naoto, Quy Tran, Phi Nguyen Chi, Long Hoang Thuy, Ha Le Dang, Ban Vo Van, Ohashi Jun, Hijikata Minako, Matsushita Ikumi, Kawana Akihiko, Yanai Hideki, Kirikae Teruo, Kuratsuji Tadatoshi, Sasazuki Takehiko
Abstract excerpt
We have hypothesized that genetic predisposition influences the progression of SARS. Angiotensin converting enzyme (ACE1) insertion/deletion (I/D) polymorphism was previously reported to show association with the adult respiratory distress syndrome, which is also thought to play a key role in damaging the lung tissues in SARS cases. This time, the polymorphism was genotyped in 44 Vietnamese SARS cases, with 103...
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