Article
Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study.
BMC infectious diseases - 9 Apr 2005
Chan K C Allen, Tang Nelson L S, Hui David S C, Chung Grace T Y, Wu Alan K L, Chim Stephen S C, Chiu Rossa W K, Lee Nelson, Choi K W, Sung Y M, Chan Paul K S, Tong Y K, Lai S T, Yu W C, Tsang Owen, Lo Y M Dennis
Abstract excerpt
BACKGROUND: It has been postulated that genetic predisposition may influence the susceptibility to SARS-coronavirus infection and disease outcomes. A recent study has suggested that the deletion allele (D allele) of the angiotensin converting enzyme (ACE) gene is associated with hypoxemia in SARS patients. Moreover, the ACE D allele has been shown to be more prevalent in patients suffering from adult respiratory...
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