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Article

A hypothetical anti-neoplastic mechanism associated to reserve cells.

Journal of theoretical biology - 21 Nov 2004

Torres-Montaner Antonio, Hughes David

Abstract excerpt

Reserve-stem cells, the permanent cells of body tissues, are thought to be the progenitor cells of cancer. This concept originates from the assumption that accumulation of somatic mutations necessary for malignant transformation can only take place in cellular targets with a prolonged life span....

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Identifiers

PMID: 15380388
DOI: 10.1016/j.jtbi.2004.06.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15380388-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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