Article
cDNA microarray-based identification of genes and pathways associated with oxaliplatin resistance.
Cancer chemotherapy and pharmacology - 1 Jan 2005
Samimi Goli, Manorek Gerald, Castel Rob, Breaux James K, Cheng Tim C, Berry Charles C, Los Gerrit, Howell Stephen B
Abstract excerpt
In order to identify genes whose expression is associated with resistance to the chemotherapeutic agent oxaliplatin, transcripts differentially expressed between an oxaliplatin sensitive and a stably resistant subline were compared in six independent replicates using Stanford cDNA microarrays for five cell lines. "Significance analysis of microarrays" (SAM) was used to identify genes whose expression was...
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