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A highly annotated database of genes associated with platinum resistance in cancer

13 Oct 2021

Abstract excerpt

Platinum-based chemotherapy, including cisplatin, carboplatin, and oxaliplatin, is prescribed to 10-20% of all cancer patients. Unfortunately, platinum resistance develops in a significant number of patients and is a determinant of clinical outcome. Extensive research has been conducted to understand and overcome platinum resistance, and mechanisms of resistance can be categorized into several broad biological...

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PMID: 34645978
DOI: 10.1038/s41388-021-02055-2

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