Article
Absence of mutations in the PCI gene in subfertile men.
Molecular human reproduction - 1 Nov 2004
Gianotten Judith, Schimmel Alinda W M, van der Veen Fulco, Lombardi M Paola, Meijers Joost C M
Abstract excerpt
The molecular aetiology of male subfertility is still unknown in the majority of cases and it is thought that multiple genes are involved. One of the genes that might play a role in male reproductive function is the protein C inhibitor (PCI) gene. In mice the presence of PCI is an absolute requirement for reproduction. In this study we performed a mutation screen of the PCI gene in subfertile men with severe...
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