Article
Association of mutations in the zona pellucida binding protein 1 (ZPBP1) gene with abnormal sperm head morphology in infertile men.
Molecular human reproduction - 1 Jan 2012
Yatsenko Alexander N, O'Neil Derek S, Roy Angshumoy, Arias-Mendoza Paola A, Chen Ruihong, Murthy Lata J, Lamb Dolores J, Matzuk Martin M
Abstract excerpt
Nearly 7% of men are afflicted by male infertility worldwide, and genetic factors are suspected to play a significant role in the majority of these patients. Although sperm morphology is an important parameter measured in the semen analysis, only a few genetic causes of teratozoospermia are currently known. The objective of this study was to define the association between alterations in the genes encoding the...
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