Article
Biallelic mutations in spermatogenesis and centriole-associated 1 like (SPATC1L) cause acephalic spermatozoa syndrome and male infertility.
Asian journal of andrology - 1 Jan 2000
Li You-Zhu, Li Na, Liu Wen-Sheng, Sha Yan-Wei, Wu Rong-Feng, Tang Ya-Ling, Zhu Xing-Shen, Wei Xiao-Li, Zhang Xiao-Ya, Wang Yi-Feng, Lu Zhong-Xian, Zhang Fu-Xing
Abstract excerpt
Acephalic spermatozoa syndrome is a rare type of teratozoospermia that severely impairs the reproductive ability of male patients, and genetic defects have been recognized as the main cause of acephalic spermatozoa syndrome. Spermatogenesis and centriole-associated 1 like (SPATC1L) is indispensable for maintaining the integrity of sperm head-to-tail connections in mice, but its roles in human sperm and early...
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