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Article

Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes.

The Journal of biological chemistry - 3 Dec 2004

de Fourmestraux Valérie, Neubauer Heike, Poussin Carine, Farmer Pierre, Falquet Laurent, Burcelin Rémy, Delorenzi Mauro, Thorens Bernard

Abstract excerpt

Genetically homogenous C57Bl/6 mice display differential metabolic adaptation when fed a high fat diet for 9 months. Most become obese and diabetic, but a significant fraction remains lean and diabetic or lean and non-diabetic. Here, we performed microarray analysis of "metabolic" transcripts expressed in liver and hindlimb muscles to evaluate: (i) whether expressed transcript patterns could indicate changes in...

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Identifiers

PMID: 15377667
DOI: 10.1074/jbc.M408014200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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