Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential.

Blood - 15 Jan 2005

Vodyanik Maxim A, Bork Jack A, Thomson James A, Slukvin Igor I

Abstract excerpt

Embryonic stem (ES) cells have the potential to serve as an alternative source of hematopoietic precursors for transplantation and for the study of hematopoietic cell development. Using coculture of human ES (hES) cells with OP9 bone marrow stromal cells, we were able to obtain up to 20% of CD34+ cells and isolate up to 10(7) CD34+ cells with more than 95% purity from a similar number of initially plated hES...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD34
Share to Erythroid-Specific DNA-Binding Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GATA1 Transcription Factor

Share to GATA2 Transcription Factor

Share to Hematopoiesis

Share to Stromal Cells

Share to T-Cell Acute Lymphocytic Leukemia Protein 1

Share to Vascular Endothelial Growth Factor Receptor-2

Source

Identifiers

PMID: 15374881
DOI: 10.1182/blood-2004-04-1649

Genes

TAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential.PMID 15374881Read ↗

Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures.Semantic proximity Read ↗

Hematoendothelial Differentiation of Human Embryonic Stem CellsSemantic proximity Read ↗

Single-cell qPCR facilitates the optimization of hematopoietic differentiation in hPSCs/OP9 coculture system.Semantic proximity Read ↗

Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co‐express gamma and beta globinsSemantic proximity Read ↗

In vitro development of a hemangioblast from a human embryonic stem cell, SNUhES#3.Semantic proximity Read ↗

Efficient Hematopoietic Differentiation of Human Embryonic Stem Cells on Stromal Cells Derived from Hematopoietic NichesSemantic proximity Read ↗

Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36.Semantic proximity Read ↗

Human Pluripotent Stem Cells Differentiated in Fully Defined Medium Generate Hematopoietic CD34+ and CD34− Progenitors with Distinct CharacteristicsSemantic proximity Read ↗

Optimization of seeding density of OP9 cells to improve hematopoietic differentiation efficiencySemantic proximity Read ↗

Prospective isolation of human clonogenic common myeloid progenitorsSemantic proximity Read ↗

Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture systemSemantic proximity Read ↗

A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.