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Article

The highly conserved extracellular peptide, DSYG(893-896), is a critical structure for sodium pump function.

European journal of biochemistry - 1 Oct 2004

Becker Susanne, Schneider Heike, Scheiner-Bobis Georgios

Abstract excerpt

The peptide sequence DSYG(893-896) of the sheep sodium pump alpha 1 subunit is highly conserved among all K(+)-transporting P-type ATPases. To obtain information about its function, single mutations were introduced and the mutants were expressed in yeast and analysed for enzymatic activity, ion recognition, and alpha/beta subunit interactions. Mutants of Ser894 or Tyr895 were all active. Conservative...

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Identifiers

PMID: 15373828
DOI: 10.1111/j.1432-1033.2004.04305.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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