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Article

Expression of ABCA3, a causative gene for fatal surfactant deficiency, is up-regulated by glucocorticoids in lung alveolar type II cells.

Biochemical and biophysical research communications - 15 Oct 2004

Yoshida Ichiro, Ban Nobuhiro, Inagaki Nobuya

Abstract excerpt

We have shown previously that the ATP-binding cassette transporter ABCA3 is expressed predominantly at the limiting membrane of the lamellar bodies in lung alveolar type II cells. Very recently, an ABCA3 gene mutation was reported in human newborns with fatal surfactant deficiency. In the present study, we have shown in rat lung that expression of the ABCA3 protein is dramatically increased after embryonic day...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dexamethasone

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Source

Identifiers

PMID: 15369786
DOI: 10.1016/j.bbrc.2004.08.133

Genes

ABCA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of ABCA3, a causative gene for fatal surfactant deficiency, is up-regulated by glucocorticoids in lung alveolar type II cells.PMID 15369786Read ↗

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