Article
Isogenic auxotrophic mutant strains in the Aspergillus fumigatus genome reference strain AF293.
Archives of microbiology - 1 Nov 2004
Xue Tao, Nguyen Cuong K, Romans Angela, Kontoyiannis Dimitrios P, May Gregory S
Abstract excerpt
Aspergillus fumigatus is a ubiquitous fungus that is a frequent opportunistic pathogen in immunosuppressed patients. Because of its role as a pathogen, it is of considerable experimental interest. A set of auxotrophic isogenic strains in the A. fumigatus genome reference strain AF293 has been developed. Using molecular genetic methods, arginine and lysine auxotrophs were made by deletion of argB and lysB,...
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