Article
A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant.
Brain research - 8 Oct 2004
Morley Barbara J, Rodriguez-Sierra Jorge F
Abstract excerpt
The alpha7 nicotinic acetylcholine receptor (nAChR) is heavily expressed in the mammalian brain. On a molecular level, the alpha7 nAChR may have a diversity of functions, but it is not known if these molecular events translate into phenotypes. The null mutant mouse is viable and generally normal. Here, we report a phenotype for the alpha7 nAChR null mutant mouse. The alpha7 nAChR is obligatory for the...
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