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Neuroendocrine control of female reproductive function by the activin receptor ALK7

5 Sept 2012

Abstract excerpt

Activins are critical components of the signaling network that controls female reproduction. However, their roles in hypothalamus, and the specific functions of their different receptors, have not been elucidated. Here, we investigated the expression and function of the activin receptor ALK7 in the female reproductive axis using Alk7-knockout mice. ALK7 was found in subsets of SF1-expressing granulosa cells in...

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PMID: 22954591
DOI: 10.1096/fj.11-199059

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