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Article

Enzyme polymorphisms, smoking, and human reproduction. A study of human placental alkaline phosphatase.

American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000

Magrini A, Bottini N, Gloria-Bottini F, Stefanini L, Bergamaschi A, Cosmi E, Bottini E

Abstract excerpt

We investigated the possible effects of placental alkaline phosphatase (PLAP) genotype on the deleterious action of maternal smoke on intrauterine survival and birthweight. PLAP is a highly polymorphic enzyme with several alleles associated with different enzymatic activities. PLAP is produced by the embryo and is found in maternal blood, where it is responsible for the rise of serum alkaline phosphatase during...

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PMID: 14595869
DOI: 10.1002/ajhb.10213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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