Article
Chagas disease: role of parasite genetic variation in pathogenesis.
Expert reviews in molecular medicine - 5 Mar 2002
Macedo Andra M, Oliveira Riva P, Pena Srgio D J
Abstract excerpt
Chagas disease, caused by the parasite protozoan Trypanosoma cruzi, is characterised by a variable clinical course, from symptomless cases to severe chronic disease with cardiac and/or gastrointestinal involvement. This variability has been attributed both to differences in the host response and to genomic heterogeneity of the parasite. This article reviews the evidence in favour of an important role of the...
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