Article
DNA polymorphisms at the lipoprotein lipase gene and their association with quantitative variation in plasma high-density lipoproteins and triacylglycerides.
Human biology - 1 Jun 1994
Mitchell R J, Earl L, Bray P, Fripp Y J, Williams J
Abstract excerpt
Lipoprotein lipase (LPL) plays a critical role in the metabolism of lipoproteins because this enzyme hydrolyzes the triacylglycerides in chylomicrons and very low density lipoproteins. This process influences the production of high-density lipoprotein (HDL), which takes up tissue cholesterol for transport to the liver for excretion. Accordingly, LPL qualifies as a candidate gene for understanding lipid metabolic...
Topics
- Adult
- Aged
- Analysis of Variance
- DNA
- Genetic Variation
- Genetics, Population
- Genotype
- Humans
- Hyperlipidemias
- Lipoprotein Lipase
- Lipoproteins, HDL