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Article

The clinical significance of the POLG gene polymorphism in male infertility.

The Journal of clinical endocrinology and metabolism - 1 Sept 2004

Krausz C, Guarducci E, Becherini L, Degl'Innocenti S, Gerace L, Balercia G, Forti G

Abstract excerpt

Based on association studies, an increasing number of gene polymorphisms have been proposed as modulators of spermatogenesis. Interestingly, a clear cause-effect relationship between a polymorphism of the POLG gene and oligo(astheno)zoospermia was recently described. The POLG gene contains a polymorphic CAG repeat, and the presence of a homozygous mutant (not10/not10 CAG) genotype was found only in infertile men....

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Identifiers

PMID: 15356024
DOI: 10.1210/jc.2004-0008

Genes

POLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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