Article
CAG repeat variation in the mtDNA polymerase gamma is not associated with oligoasthenozoospermia.
International journal of andrology - 1 Dec 2009
Rani Deepa Selvi, Carlus S Justin, Poongothai J, Jyothi Amara, Pavani Kadupa, Gupta Nalini J, Reddy Alla G, Rajan M Mamtha, Rao Kamini, Chakravarty Baidyanath, Singh Lalji, Thangaraj Kumarasamy
Abstract excerpt
Variations in the trinucleotide-CAG repeat number of the catalytic subunit of the mitochondrial DNA polymerase gamma (POLG) have been speculated to be associated with male infertility. The ten CAG repeats (10/10) were found to be the most common allele (88%), absence of which was found to be associated with male infertility. As no study on Indian population was conducted so far to support this view, we...
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