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Article

Analysis of 6 single-nucleotide polymorphisms in the androgen receptor gene in Chilean patients with primary spermatogenic failure.

Journal of andrology - 1 Jan 2000

Parada-Bustamante Alexis, Lardone María Cecilia, Valdevenito Raúl, Ebensperger Mauricio, López Patricia V, Madariaga Marcia, Piottante Antonio, Castro Andrea

Abstract excerpt

Androgens are essential for spermatogenesis. It has been postulated that androgen activity is modulated directly or indirectly by genetic variability in the androgen receptor gene sequence, including CAG/GGN polymorphisms and single-nucleotide polymorphisms (SNP). In this study, the frequency of 6 SNPs that constitute a haplotype in the androgen receptor sequence was determined by enzyme restriction assays...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21393548
DOI: 10.2164/jandrol.110.012195

Genes

GGN
HAP1

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