Article
Escherichia coli strains blocked in Tat-dependent protein export exhibit pleiotropic defects in the cell envelope.
Journal of bacteriology - 1 Jan 2001
Stanley N R, Findlay K, Berks B C, Palmer T
Abstract excerpt
The Tat system is a recently discovered protein export pathway that serves to translocate folded proteins, often containing redox cofactors, across the bacterial cytoplasmic membrane. Here we report that tat strains are associated with a mutant cell septation phenotype, where chains of up to 10 cells are evident. Mutant strains are also hypersensitive to hydrophobic drugs and to lysis by lysozyme in the absence...
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