Article
Saccharomyces cerevisiae and Neurospora crassa contain heavy metal sequestering phytochelatin.
Archives of microbiology - 1 Jan 1992
Kneer R, Kutchan T M, Hochberger A, Zenk M H
Abstract excerpt
In fungi, cellular resistance to heavy metal cytotoxicity is mediated either by binding of metal ions to proteins of the metallothionein type or by chelation to phytochelatin-peptides of the general formula (gamma-Glu-Cys)n-Gly. Hitherto, only one fungus, Candida glabrata has been shown to contain both metal inactivating systems. Here we show by unambiguous FAB-MS analysis that both a metallothionein-free mutant...
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