Article
A role for HEM2 in cadmium tolerance.
Journal of inorganic biochemistry - 1 Mar 1998
Hunter T C, Mehra R K
Abstract excerpt
A Candida glabrata cadmium-sensitive mutant partially defective in glutathione production and exhibiting a complete absence of phytochelatins was used to clone a gene required for Cd tolerance. Transformation of the Cd-sensitive mutant with a genomic library from the wild-type C. glabrata led to...
Topics
- Amino Acid Sequence
- Animals
- Cadmium
- Candida
- Cloning, Molecular
- Drug Resistance, Microbial
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Glutathione
- Heme
- Humans
- Metalloproteins
- Mice
- Molecular Sequence Data
- Mutation
- Phytochelatins
- Plant Proteins