Article
[Catatonia or depression: the GC rat strain as an animal model of psychopathology].
Genetika - 1 Jun 2004
Kolpakov V G, Kulikov A V, Alekhina T A, Chuguĭ V F, Petrenko O I, Barykina N N
Abstract excerpt
The utility of "incomplete" genetic animal models of human diseases, in particular, psychoses, is discussed. The GC rat strain selected for predisposition to cataleptic reactions is described. It is shown that in many of their characteristics, GC rats are similar to schizophrenic and depressive patients. A possibility that akinetic catatonic states and depressions, hyperkinetic catatonic states and mania share...
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