Article
[Architecture of the X chromosome, expression of LIM kinase 1, and recombination in the agnostic mutants of Drosophila: a model of human Williams syndrome].
Genetika - 1 Jun 2004
Savvateeva-Popova E V, Peresleni A I, Sharagina L M, Medvedeva A V, Korochkina S E, Grigor'eva I V, Diuzhikova N A, Popov A V, Baricheva E M, Karagodin D, Heisenberg M
Abstract excerpt
As the Human Genome and Drosophila Genome Projects were completed, it became clear that functions of human disease-associated genes may be elucidated by studying the phenotypic expression of mutations affecting their structural or functional homologs in Drosophila. Genomic diseases were identified as a new class of human disorders. Their cause is recombination, which takes place at gene-flanking duplicons to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.