Article
ABO blood type, Lewis and Secretor genotypes, and chronic atrophic gastritis: a cross-sectional study in Japan.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jan 2003
Shibata Atsuko, Hamajima Nobuyuki, Ikehara Yuzuru, Saito Toshiko, Matsuo Keitaro, Katsuda Nobuyuki, Tajima Kazuo, Tatematsu Masae, Tominaga Suketami
Abstract excerpt
BACKGROUND: the H type I structure, synthesized by the secretor (Se) enzyme in gastric foveolar cells, and its metabolite, Lewis b (le(b)) antigen, mediate the adhesion of Helicobacter pylori ( H. Pylori) to the gastric epithelium, whereas H. Pylori does not bind to modified forms of Le(b) specific for blood types A and B. Such host factors as Le and Se genotypes and ABO blood type may affect the establishment of...
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