Article
Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2004
Schuessel K, Leutner S, Cairns N J, Müller W E, Eckert A
Abstract excerpt
Since oxidative stress plays an important role in the pathogenesis of Alzheimer's disease (AD) and since the age-adjusted incidence of AD is higher in females than males, we examined a possible influence of gender on antioxidant metabolism in brains from male and female AD patients and age-matched controls. Activities of copper/zinc-dependent superoxide dismutase (SOD), glutathione peroxidase (GPx) and...
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