Article
Hepatitis B genotypes and precore/basal core promoter mutants in HBeAg-negative chronic hepatitis B.
Journal of gastroenterology - 1 Jan 2002
Lin Chih-Lin, Liao Li-Ying, Liu Chun-Jen, Chen Pei-Jer, Lai Ming-Yang, Kao Jia-Horng, Chen Ding-Shinn
Abstract excerpt
BACKGROUND: Mutations in the precore stop codon (G1896A) and the basal core promoter (A1762T and G1764A) are frequently found in hepatitis B envelope antigen (HBeAg)-negative chronic hepatitis B. However, the clinical significance of these mutations remains controversial. We therefore investigated the influence of hepatitis B virus (HBV) genotypes, as well as precore/basal core promoter mutants, on the clinical...
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