Article
Lack of association between RNASEL Arg462Gln variant and the risk of breast cancer.
Anticancer research - 1 Jan 2000
Sevinç Akin, Yannoukakos Drakoulis, Konstantopoulou Irene, Manguoglu Esra, Lüleci Güven, Colak Taner, Akyerli Cemaliye, Colakoglu Gülsen, Tez Mesut, Sayek Iskender, Gerassimos Voutsinas, Nasioulas George, Papadopoulou Eirene, Florentin Lina, Kontogianni Elena, Bozkurt Betül, Kocabas Neslihan Aygün, Karakaya Ali Esat, Yulug Isik G, Ozçelik Tayfun
Abstract excerpt
BACKGROUND: The RNASEL G1385A variant was recently found to be implicated in the development of prostate cancer. Considering the function of RNase L and the pleiotropic effects of mutations associated with cancer, we sought to investigate whether the RNASEL G1385A variant is a risk factor for breast cancer. PATIENTS AND METHODS: A total of 453 breast cancer patients and 382 age- and sex-matched controls from...
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