Article
Role of genetic polymorphisms of the RNASEL gene on familial prostate cancer risk in a Japanese population.
British journal of cancer - 18 Aug 2003
Nakazato H, Suzuki K, Matsui H, Ohtake N, Nakata S, Yamanaka H
Abstract excerpt
The RNASEL gene on chromosome 1q25 has been identified as a prostate cancer susceptibility gene. We screened for RNASEL germline mutations in familial prostate cancer patients, and performed a case-control study to examine the association of specific variants with prostate cancer risk in the Japanese. Three variants within the RNASEL gene, G282A, G1385A and T1623G were identified. G1385 and T1623G variants result...
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