Article
TERC is not a major gene in human neural tube defects.
Birth defects research. Part A, Clinical and molecular teratology - 1 Aug 2004
Benz Lisa P, Swift Frances E, Graham Felicia L, Enterline David S, Melvin Elizabeth C, Hammock Preston, Gilbert John R, Speer Marcy C, Bassuk Alexander G, Kessler John A, George Timothy M
Abstract excerpt
BACKGROUND: Neural tube defects (NTDs) are the second most common birth defects, after congenital heart defects. Telomerase, the reverse transcriptase that maintains telomere DNA, has been shown to be important for neural tube development and bilateral symmetry in the brain. In knockout mice null...
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